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A randomized, double-blind, crossover pilot trial published in the journal Nutrients found that 100-200mg of dihydroberberine achieved plasma berberine levels approximately 5 times higher than 500mg of standard berberine (measured by area under the curve)

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Deficiency in glutathione or its cofactors, including selenium and riboflavin, may contribute to the progression of autoimmune thyroid conditions such as Hashimotos thyroiditis (1,2)

Vasireddi and colleagues at the Hospital for Special Surgery published the most rigorous accounting of BPC-157 literature to date in 2025