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CPT increased NDUFS3-NDUFV1 interaction and reduced aberrant NDUFS3 interactions with NDUFV2 and Notch2, indicating direct inhibition of RET through conformation changes of complex I architecture

Preclinical Model Research : Referenced in rodent research settings, particularly for investigating functional outcomes in ischemia/stroke-related models (for research use only)

At ~5382 Da, FOXO4-DRI is above the typical renal filtration threshold (~60 kDa for globular proteins, but much lower for linear peptides), suggesting renal clearance may contribute to elimination

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