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Individuals with the following cardiac conditions should exercise caution and may require thorough cardiovascular assessment before treatment: Uncontrolled tachyarrhythmias : Patients with poorly controlled atrial fibrillation, atrial flutter, or ventricular tachycardia may experience worsening symptoms due to the heart rate-increasing effects of these medications

It says semaglutide is contraindicated in pregnancy, in anyone with a personal or family history of medullary thyroid carcinoma, and in patients with multiple endocrine neoplasia syndrome type 2

(1998) characterized Ipamorelin as a potent and selective growth hormone secretagogue in preclinical models, distinguishing it from earlier generation GHRPs with broader endocrine effects

[1] [2] At lower doses, weight reductions were clinically meaningful, ranging from approximately 8% to 17%