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Name: semaglutide alcohol dependence New Research: Oral Reduced Heavy Drinking in Adults with Use Disorder Weight loss drug shows promise
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Using fluorescence-activated nuclei sorting to enrich for non-neuronal cells, we generated a dataset of 109,334 non-neuronal (1722 unique genes, 3216 unique transcripts) and 103,607 neuronal cells (3987 unique genes, 13,696 unique transcripts

The side effect profiles of semaglutide and tirzepatide differ enough that switching between them is a reasonable strategy

That difference is one of the main practical reasons the article gives for choosing one path over the other