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100 OrioF.Jr.TrouanneB.GeorgetV.LumbrosoS.AvancesC.SiatkaC.et al (2002)

Oral is a reasonable option for patients who cannot or will not inject, but want systemic rather than purely local effect

Oxidants, such as superoxide anion (O 2 ) and hydrogen peroxide (H 2 O 2 ), are produced by exogenous factors (i.e., drugs, infection) and also are formed within red cells as a consequence of reactions of hemoglobin with oxygen