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Owing to this, not only functionality of oxygen-responsive NPs designed to alleviate hypoxia become limited, but also hampers the effectiveness of oxygen-dependent therapies, such as photodynamic therapy (PDT)

Stupnisek et al., 2012

This reflects the chronic and relapsing nature of obesity

Stop taking CONTRAVE and call your healthcare provider or go to the nearest hospital emergency room right away if you have any of the following signs and symptoms of an allergic reaction: rash, itching, hives, fever, swollen lymph glands, painful sores in your mouth or around your eyes, swelling of your lips or tongue, chest pain, or trouble breathing