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Eating lighter on peak days (when appetite suppression is strongest) and slightly more on trough days (when appetite returns) can smooth out the nutritional experience while the plotter shows you the pharmacokinetic rationale behind the strategy
Similarly, the STEP UP Obesity trial revealed that about 33% of patients on the 7.2 mg dose lost 25% or more of their starting weight, while only 15% of those on the lower dose achieved the same level of weight loss
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