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For longer storage, solutions may be aliquoted into smaller sterile vials and frozen at -20 degrees C or lower to avoid repeated freeze-thaw cycles.
To give tirzepatide users and compounding pharmacies time to prepare, the FDA provided a ramp-off transition period from December 2024 to March 19, 2025
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Based on class data from authorised GLP-1 RA SmPCs, prescribers should consider therapeutic drug monitoring or clinical assessment when initiating retatrutide in patients taking medicines such as: Digoxin used for heart failure and atrial fibrillation
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