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Another small-scale study of 253 older T2DM patients with and without AD yielded a similar conclusion that DPP4i use was associated with better cognitive performance compared with metformin (mean [SD] change in MMSE score in sitagliptin group versus metformin group over 6 months in patients without AD: 0.95 2.17 versus 2.50 3.03) (Isik et al., 2017)
The SUSTAIN-6 trial found that Ozempic reduced the risk of major cardiovascular events like heart attack, stroke, and cardiovascular death by 26%
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