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The situation with the spread of antibiotic-resistant bacteria and the resulting infections and deaths worsened between 2016 and 2020 in the EU countries, leading to increased healthcare costs
Network pharmacology enhances the precision of drug discovery by linking pharmacological targets to disease mechanisms through target prediction algorithms and functional enrichment analyses, such as Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway mapping (Singh et al., 2022)
MetaboAnalyst 6.0 ( online platform was used for NMR bioinformatic analyses
BPC 157 can enhance the expression and endocytosis of VEGFR2, and subsequently the phosphorylation of AKT and eNOS as proved in our previous study 6
