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172 Natural compounds such as curcumin, quercetin, and salvianolic acid B have also demonstrated transporter-inhibitory properties with relatively low toxicity, although issues with solubility and bioavailability have limited their clinical utility and prompted formulation optimization

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This is despite an average BMI of 35a data point found within clinician notes in the EMRplacing them squarely within the population clinically eligible for existing injectable therapies