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The Cu refers to copper, the peptide binds a copper ion, and that copper-binding property is central to its biological function
Li B, Liao Y-H, Cheng X, et al
Spinocerebellar ataxia type 2 Spinocerebellar ataxia type 2a genetic neurodegenerative disorder due to a CAG repeat expansion mutation in the ATXN2 gene coding for the protein ataxin-2 63 has been associated to oxidative stress, in particular due to alterations in the enzymatic activity of antioxidant enzymes including GSTs 64
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