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2003 May;24(2):47-66
Tirzepatide causes gastrointestinal symptoms including nausea, vomiting, diarrhea, and constipation in a substantial percentage of users, particularly during dose escalation phases
It is worth noting that the effectiveness of -GlcA-N1/E4 was indistinguishable from the SC2S control treatment group, where a matching concentration of the purified dimer was given intratumourally, from which one could infer that the efficiency of dimer formation from the prodrug system was not the limiting factor of its efficacy
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