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However, the improvements we observed in overall cognition composite of NIH Toolbox with l-theaninecaffeine combination is not surprising given that multiple interventional trials and meta-analyses of such trials have suggested that particularly the combination of l-theanine and caffeine seems to improve a variety of cognitive functions 25,26,27,33,36,37
Gao F, Chen J, Ma T, Li H, Wang N, Li Z, Zhang Z, Zhou Y (2014) The glutathione peroxidase gene family in Thellungiella salsuginea: genome-wide identification, classification, and gene and protein expression analysis under stress conditions
However, the conclusions that can be drawn from the included studies are significantly limited given small sample size, limited follow-up time, and a lack of control groups