Concerto, C., Chiarenza, C., Di Francesco, A., Natale, A., Privitera, I., Rodolico, A., Trovato, A., Aguglia, A., Fisicaro, F., Pennisi, M., Bella, R., Petralia, A., Signorelli, M
This indicates that ASEO and DADS dose-dependently prevented obesity in mice through minimizing lipid accumulation and oxidative stress and, as a result, protected against inflammation by alleviating metabolic abnormalities in mice fed with a high-fat diet
Not advised to be used during pregnancy or breastfeeding
As pregnancy advances and the placenta develops, the expression of OCT2 in the placenta increases, which facilitates the transport of metformin through these channels