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It is a well-characterized, mechanistically specific peptide with a 30-year research history, a strong clinical safety record from formal trials, and modest but real efficacy data from 12-week studies
cost of the drug is high, or when there is a risk of dependence The price of many Schedule 4 substances are subsidized by the Australian Government through the Pharmaceutical Benefits Scheme (PBS), when prescribed by an authorised prescriber
The use of claim 28 wherein the peptide Ac-Nle-cycVo(-Asp-His-D-Phe-Arg-Trp-Lys)- OH is employed for manufacture of a medicament for treatment by nasal administration and the PDE-5 inhibitor is employed for manufacture of a medicament for treatment by oral administration
