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I profili farmacocinetici completi (assorbimento, distribuzione, metabolismo, escrezione) non sono stati completamente caratterizzati nell'uomo
Adults who tolerate 2.4 mg, still need additional weight reduction, and are accepting the higher-dose adverse-effect burden
A secondary mechanistic analysis of the SUMMIT trial found associations between tirzepatide treatment and reductions in circulatory volume and markers of cardiac injury [85]
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