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When you administer it systemically, you activate mechanisms that affect multiple organ systems

The primary source of cystine in GSH synthesis is available through the cystine-glutamate antiporter xCT

In a 2003 in vitro experiment by Khavinson and colleagues, addition of micromolar concentrations of the peptide to cultured human somatic fibroblasts produced a measurable increase in telomerase reverse transcriptase activity and a corresponding extension of telomere length across 1020 passages, with cell cultures continuing to divide beyond the Hayflick limit observed in untreated controls

This helps prevent early ageing and skin damage