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Aluminum may reach toxic levels with prolonged parenteral administration if kidney function is impaired
Hydroxocobalamin, the form most commonly used in the UK, may cause: Injection site reactions (pain, redness, or swelling) Temporary reddish discolouration of urine Rarely, hypersensitivity reactions Very rarely, hypokalaemia in severely deficient patients when treatment is initiated (potassium levels should be monitored in severe deficiency) B12 injections are considered very safe, with no upper tolerable limit established, as excess B12 is excreted in urine
The primary risk of rapid weight loss is muscle catabolism
For instance, because of its role in DNA repair, it is essential for cell division and plays a significant role in the formation and repair of all cells
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