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Some individuals may experience mild side effects such as pain or swelling at the injection site, itching, or headaches
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Alongside these, several studies focused on elucidating the role of mitogen-activated protein kinases (MAPKs) in NRF2 activation, suggested the involvement of c-jun N-terminal kinase 1/2 (JNK1/2) and extracellular signal-regulated kinase 1/2 (ERK1/2) in the NRF2 activation and nuclear accumulation [208, 209]
The findings indicated that 3 weeks of LC supplementation, in the amount 2-3 g/day, effectively alleviated pain [50,51,52,53]
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