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You suffer from a genetic condition or chronic illness that impacts your ability to lose weight

Lancet 397:18301841 Shulman A, Peltonen M, Sjstrm CD et al (2018) Incidence of end-stage renal disease following bariatric surgery in the Swedish obese subjects study

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Benefits of Activating GLP-1 Receptors By increasing endogenous GLP-1 or using agonists that mimic GLP-1, we can activate GLP-1 receptors and obtain therapeutic benefits such as the following: Weight Control and Improved Satiety GLP-1 slows digestion, suppresses appetite, and enhances metabolism to promote one to achieve optimal weight