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Hsieh and colleagues (J Mol Med, 2017) reported that BPC 157 upregulated VEGFR2 expression and promoted receptor internalisation and downstream signalling in human umbilical vein endothelial cells, with increased tube formation in vitro and greater vessel density in a rodent hindlimb ischaemia model
Easy tolerance from the first application, with no adjustment period needed, might indicate starting concentrations below your skin's capability
Pickles et al., 2013, 2016
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