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The recommended restart protocol: If you were at 1 mg or below: restart at 0.5 mg for 2 weeks, then return to your previous dose If you were at 1.7 mg or 2.4 mg: restart at 1 mg for 2 weeks, then return to your previous dose This is the same principle as initial titration

Comparative Effectiveness: Studies are underway to compare semaglutide with other GLP-1 receptor agonists and newer combination therapies to achieve optimal patient outcomes

Phase Mid escalation Weeks Weeks 9-12 Weekly Dose 4 mg Notes Appetite suppression usually becomes noticeable

The segment of patients who ceased the study in trials 1, 2, and 3 was approximately 16 % of the Semaglutide treated group