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The peptide forms a stable complex with copper ions, and this GHK-copper combination triggers gene expression changes affecting tissue regeneration , inflammation, and collagen synthesis
Available data comes primarily from animal studies, where the peptide has generally shown a very favorable toxicity profile
10.1165/rcmb.2007-0295OC
One study observed that patients with depression showed impaired neurogenesis, neural growth retardation, and synaptic plasticity reduction (Serafini, 2012)
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