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Each method has its own set of advantages and limitations, but injections are often considered the most effective due to their direct delivery into the bloodstream
In one study, people who took Semaglutide GLP-1 injections along with making lifestyle changes lost an average of 15.3% of their initial body weight over 68 weeks
The FLOW trial also highlights the renal protective effects of GLP-1RAs, suggesting a close link between renal and cardiovascular benefits, which warrants further mechanistic studies (256)
Then, the mice were imaged with 10-min static PET scanning
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