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Orforglipron Phase 3 data showed gallbladder-related events at rates modestly above placebo, consistent with the class effect
The US Food and Drug Administration has also approved certain GLP-1 medications to treat obesity
Reactions that spread beyond the immediate injection area, involve significant swelling, or are accompanied by fever or systemic symptoms require medical evaluation
Head-to-head data show tirzepatide delivers approximately 20% average weight loss versus roughly 14% for semaglutide a 47% relative advantage
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