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Gastrointestinal side effects are the defining tolerability issue for the entire incretin class, and both drugs share that profile
All treatments, including Mounjaro (tirzepatide), are prescribed following a structured clinical assessment to ensure they are safe, appropriate, and in line with UK regulatory guidance
This hormonal response helps slow gastric emptying, promote fullness, and reduce overeating after meals
The Tirzepatide half-life is estimated to be around five days (source)
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