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Using biodegradable polymeric nanoparticles (NPs) engineered for TAM targeting via CD206 mannose receptor binding, researchers delivered in vitro -transcribed mRNA encoding IRF5, a transcription factor crucial for M1 polarization, and its activating kinase, IKK

Methods Patients were randomly assigned to either the observation group or the control group using a computer-generated random number table created using SPSS software (version 21.0)

The conservative approach involves using DSIP for defined periods (10 to 20 days) followed by equal or longer breaks, similar to other peptide cycling strategies

ROC analysis evaluated diagnostic performance