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Elevated NNMT is linked to: Reduced NAD+ availability Slower mitochondrial function Increased fat storage efficiency Higher risk for insulin resistance By reducing NNMT activity, 5-Amino-1MQ allows the body to maintain higher NAD+ levels, which can support better mitochondrial performance, improved fat oxidation, and more balanced energy metabolism
This is why most practitioners who recommend oral glutathione now favour liposomal forms over standard capsules
Bottom line Transitioning from Ozempic to Mounjaro can lead to better blood sugar control and more weight loss, as Mounjaro has shown greater reductions in HbA1c and up to 20% weight loss
