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The administration of GLP-1RA or exendin-4 to rats fed a high-fat diet resulted in an increase in the OPG/RANKL ratio and a reduction in the degree of bone loss
For instance, GLP-1 RAs appear to reduce inflammation in the ovaries and may help lower androgen levels ( 10 , 12 ), indicating potential broader effects on reproductive and metabolic health
Diabetes (2006) 55:97887
The funders had no role in study design, data collection, data analysis, decision to publish, or manuscript preparation
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