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TRAF6-mediated SM22 K21 ubiquitination promotes G6PD activation and NADPH production, contributing to GSH homeostasis and VSMC survival in vitro and in vivo
Maintenance Dose: Once B12 levels are normalized, a maintenance dose of 1,000 mcg monthly or every few months may be recommended
Monitoring, Labs, and Outcome Tracking Baseline labs typically include serum B12, methylmalonic acid (MMA), and homocysteine
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