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Moreover, it promotes HSC apoptosis, reducing their number and ECM synthesis, thereby alleviating fibrosis
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Whether this produces beneficial or detrimental effects depends on individual methylation pathway capacity, genetic polymorphisms (like MTHFR variants), and baseline homocysteine levels
doi: 10.1186/s40560-018-0340-6 106 RichterRPAshtekarARZhengLPretoriusDKaushlendraTSandersonRDet al
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