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Quick refresher: what B12 actually does Vitamin B12 (cobalamin) is a water-soluble vitamin involved in red blood cell formation, nervous system maintenance, and the methylation reactions that support energy metabolism
If digestive symptoms such as ongoing diarrhea, abdominal pain, bloating, or unexplained weight loss are present, evaluation for malabsorption may be needed
Caused most commonly by pernicious anaemia (autoimmune condition), dietary insufficiency in vegans, malabsorption disorders, or gastrointestinal surgery affecting B12 absorption
NICE advises that blood samples for diagnostic testing should generally be taken before vitamin B12 replacement is started because treatment can affect the interpretation of results
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