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doi: 10.1080/15384047.2023.2291855 29 HeJDingHLiHPanZChenQ
Animal experiments confirmed that dural injection of bone marrow mesenchymal stem cell-derived exosomes miR-367-3p significantly reduced the expression of EZH2 in spinal cord tissues of EAE mice, increased the expression of SLC7A11, GPX4, GSH, and SOD, decreased the levels of Fe 2+ and MDA, inhibited spinal cord iron deposition, ferroptosis, and inflammation, and alleviated spinal cord injury ( 2+ and MDA levels, while reducing GSH, NRF2, and GPX4 expression, as well as iron reactive element binding protein 2 (IREB2) in optic nerve tissue
Chemical Properties Source: NCBI PubChem public domain data 2D structure diagram from NCBI PubChem
muciniphila stimulates GLP-1 secretion and improves insulin sensitivity through multiple pathways, including both SCFA production and direct L-cell signaling
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