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The trajectory analysis of the SR18GLP-1R complex (Figure 11) revealed that, similar to GLP-1, SR18 also remains bound to the GLP-1R throughout the MD studies with an average of nine intermolecular hydrogen bonds
This distinction matters clinically because mechanism differences affect efficacy, side effects, and individual response patterns
Factors such as age, health status, diet, lifestyle, and adherence to usage guidelines can influence outcomes
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