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[3] The regulation of levels of ROS, levels of oxidized and reduced glutathione and other thiols, and antioxidant enzymes (such as GSTs and glutathione reductase) are important in determination of the most stable conditions for redox control, or for activation of apoptosis

The induction of oxidative cell death emerges as a key strategy in the field of cancer therapeutics

The emerging hallmarks of cancer metabolism

REFERENCES Bick JA, Setterdahl AT, Knaff DB, Chen Y, Pitcher LH, Zilinskas BA, Leustek T (2001) Regulation of the plant-type 5-adenylyl sulfate reductase by oxidative stress