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Importantly, a pilot study in older adults with T2DM and obesity reported that semaglutide preserved the SMM percentage of the extremities despite a decrease in total muscle mass [55]

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But GLP-1 and its agonists also activate GLP-1 receptors in the gut and brain that cause you to feel hungry before eating and no longer hungry (sated) after eating

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The improved absorption might eliminate the irritation caused by unabsorbed ingredients

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Considering muscle mass maintenance and the putatively beneficial effects of ketosis, KDs and STS should be compared with chronic CR or protein restriction in clinical studies

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