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Five to ten percent of patients discontinued the drug across doses, the company said, which was one of two late-stage trials the drug must pass before being submitted for federal approval

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Side Effects Gastrointestinal Issues: Nausea, vomiting, and diarrhea are the most common, especially during the first few weeks

Hyposalivation, a related but distinct condition, refers to objectively reduced salivary flow, typically measured at less than 0.1 mL per minute for unstimulated whole saliva