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Patients taking GLP-1 therapy often have underlying conditions such as obesity and diabetes that independently increase thrombotic risk
The most commonly reported effects include: Nausea the most common, typically peaks in the first 48 weeks and decreases significantly as the body adjusts Reduced appetite expected and intentional
The SURPASS-1 trial investigated the efficacy and safety of the three doses of 5, 10, or 15 mg tirzepatide in drug-nave patients with T2D who were not sufficiently controlled with a lifestyle intervention with diet and exercise versus placebo (70)
The effect of aging on glutathione metabolism
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