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[4] Where published studies do not report a toxicological signal, the correct interpretation is not reported under the tested experimental conditions, not fully excluded. This distinction is important because many published studies involving 5-Amino-1MQ were designed primarily to evaluate NNMT-related biological mechanisms or model-specific metabolic endpoints, rather than to serve as dedicated toxicology programs
While large population studies are mostly limited to epidurals and PNBs, there are numerous reports describing LAST with other types of local anesthesia
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