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Liraglutide did not significantly inhibit pyroptosis in BV2 cells in vitro, although its protective properties in a mouse model of EAE appear to be related to AMPK regulation, autophagy and inhibition of pyroptosis [265]
In practical terms, that means the typical individual in Mississippi would need to spend roughly one-eighth of their annual income to maintain continuous GLP-1 treatment, a cost so steep it would likely require cutting back on essentials or major lifestyle expenses just to afford it
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