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Murphy and George Minot for discovery of an effective treatment for pernicious anemia using liver concentrate, later found to contain a large amount of vitamin B 12

Researchers who need to reason about dosing frequency in an experimental model generally rely on the exposure and dosing schedules reported in the specific animal papers rather than on a defined human-style half-life, and route decisions are governed by their study design

When starting B12 injections, regular medical and blood tests will help determine the appropriate future dosage and schedule

Underlying Medical Conditions Liver disease Kidney disease Blood disorders Certain cancers 3