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In this study, all early and late phase markers of odonto/osteogenic differentiation were highly expressed in IGF-1-treated SCAPs with the low-expression of hsa-let-7c , but significantly downregulated in Let-7c overexpression group, indicating that hsa-let-7c was paramount to the IGF-1/IGF-1R/ hsa-let-7c axis

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Vitamin B-12 deficiency According to a fatigue anemia shortness of breath feeling dizzy or light-headed neurological problems A 2017 case study reported that about 10 percent of people with vitamin B-12 deficiency have darkened knuckles

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