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Higher Discontinuation Rates: The triplet therapy group had a 28.3% discontinuation rate due to tolerability issues and adverse events, significantly higher than the 4% to 10% seen in the semaglutide-only or semaglutide + trevogrumab groups

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Continuing Metformin While Starting Semaglutide Injections If you are already taking metformin, there is no requirement to stop it when beginning semaglutide therapy

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