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Lillys orforglipron, if approved as expected this month, will not only end Novos brief run as the only oral GLP-1 game in town, but it also comes with what may well be a consumer-friendly competitive edge

In patients with type 2 diabetes, semaglutide exposure increases in a dose-proportional manner for once-weekly doses of 0.5 mg and 1 mg

She also noted that the drugs slow down digestion, which could give the stomach more time to break down food and produce gas

The practical protocol approach for most researchers starts at a lower dose, typically 2mg weekly, and escalates every three to four weeks based on tolerance