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Bring it to your healthcare provider and specifically ask: "Which of these can cause weight gain, and are there weight-neutral alternatives?" The medications most likely to interfere were listed earlier: antipsychotics, certain antidepressants, corticosteroids, insulin, sulfonylureas, gabapentin, pregabalin, beta-blockers, lithium, and valproate

Some of the ways this medication affects metabolism include: Blood sugar regulation Semaglutide GLP-1 works by stimulating the release of insulin and reducing the secretion of glucagon, which helps lower and regulate blood sugar levels

AUC 0-24h , semaglutide and C max,semaglutide were approximately 70% higher when dosed with 50 versus 240 mL water[2]