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The restraints for the N-terminal lipid modification of Cagri were generated by the electronic Ligand Builder and Optimization Workbench (eLBOW) in PHENIX
The ability of resveratrol to modulate sirtuin-1 (SIRT1) and suppress acetylation of p53, a pro-apoptotic protein, has also been evidenced (Sin et al., 2014)
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