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Hormonal changes can affect collagen and skin elasticity
IGF-1 Side Effects IGF-1 supplements have been linked to serious side effects such as (7, 13): swelling of the extremities low blood sugar headaches joint pain heart enlargement increased cancer risk hormone dysfunction acne
Exposure to greater than 25 mg may precipitate a hypertensive crisis , marked by a rapid rise in blood pressure (often exceeding 180/120 mmHg), chest pain, and acute confusion
Activation of IGF pathways influences glucose uptake, nutrient utilization, and energy partitioning at the cellular level
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