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This allowed us to isolate the effect of prolonged stress on fear extinction, demonstrating that PTSD-model mice (fear conditioning + SPS) exhibited impaired extinction retrieval compared to the footshock-only group, despite acquiring similar levels of fear during conditioning

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Ca 2+ /calmodulin-kinase II enhances channel conductance of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate type glutamate receptors