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Animal studies show that mast cell stabilizing agents (cromolyn and ketotifen) can reduce both obesity and diabetes

Saaoud F, Liu L, Xu K, et al

On the other hand, the decrease in HbA1c and body weight at EOS in those patients who had already been treated with other GLP-1RAs, although noteworthy, was lower than that reported for those patients nave to GLP-1RA, whose proportion ranged between 30% and 40% in both no/low CKD risk and CKD cohorts